Levels of protein structure shown by the haemoglobin molecule

1HGC "half oxy" haemoglobin
Amino acid colour codes: ASP, GLU, CYS, MET, LYS, ARG, SER, THR, PHE, TYR, ASN, GLN, GLY, LEU, VAL, ILE, ALA, TRP, HIS and PRO.
PRIMARY STRUCTURE

Initial view shows one of the a chains as a smooth trace, coloured by residues (see above)

Name a chain residues on a trace

Number a chain residues on a trace

Unlabel residues

SECONDARY STRUCTURE

Ribbon display a chain

Cartoon format a chain

Show / hide a chain molecular detail

Show / hide a chain hydrogen bonds

QUATERNARY STRUCTURE

Show all 4 chains as ribbons, traces , all 4 haems

FUNCTION: OXYGEN STORAGE WITHIN RED BLOOD CELLS

Show oxygens (spacefill) - only on the 2 alpha chains

DISPLAY

Start /stop rotation


This graphics display was prepared to support a unit on the levels of protein structure using haemoglobin as an example.

Reference: Liddington, R., Derewenda, Z., Dodson, E., Hubbard, R., Dodson, G. High resolution crystal structures and comparisons of T-state deoxyhaemoglobin and two liganded T-state haemoglobins: T(alpha-oxy)haemoglobin and T(met)haemoglobin. J.Mol.Biol. v228 pp.551-579 , 1992 [ PDB Abstract ]

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