Animation of enzyme action at higher temperature

The conversion of substrate to product is speeded up at higher temperature, due to faster diffusion and molecular activity.
This means that there are more collisions between substrate and enzyme, forming more enzyme-substrate complexes per unit time, i.e the rate of reaction is increased.
This increase is only achieved if the enzyme is not damaged by heat.
If its molecular structure - particularly its active site - is damaged, it is said to be denatured.

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